5-HT2B receptor - definição. O que é 5-HT2B receptor. Significado, conceito
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O que (quem) é 5-HT2B receptor - definição


5-HT2B receptor         
MAMMALIAN PROTEIN FOUND IN HOMO SAPIENS
HTR2B; 5-HT2B; 5HT2B receptor; HTR2B (gene)
5-Hydroxytryptamine receptor 2B (5-HT2B) also known as serotonin receptor 2B is a protein that in humans is encoded by the HTR2B gene. 5-HT2B is a member of the 5-HT2 receptor family that binds the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).
5-HT1 receptor         
TRANSMEMBRANE PROTEIN
5-HT1; 5-ht1; 5-ht1 receptor; 5HT1B
The 5-HT1 receptors are a subfamily of the 5-HT serotonin receptors that bind to the endogenous neurotransmitter serotonin (also known as 5-hydroxytryptamine, or 5-HT). The 5-HT1 subfamily consists of five G protein-coupled receptors (GPCRs) that are coupled to Gi/Go and mediate inhibitory neurotransmission, including 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E, and 5-HT1F.
5-HT3 receptor         
  • '''Figure 3. The cDNA sequence of the mouse 5HT3 receptor'''. The cDNA encodes a 122 nucleotide 5' UTR and a ~510 nucleotide 3' UTR. Boxes indicate exons and the numbers below the exons indicate their length. For instance, the first exon encodes 22 amino acids plus one nucleotide belonging to a split codon with another 2 nucleotides encoded by the next exon. M1-4 indicate the transmembrane helices and C-C indicates the Cysteine loop. Modified after Uetz et al. 1994<ref name=Uetz_1994/>
  • '''Figure 1. The subunits are assembled as a pentamer (right) and each subunit has four transmembrane domains (left).'''
INTERPRO FAMILY
5-HT 3 receptors; 5-HT3; 5HT3 receptor
The 5-HT3 receptor belongs to the Cys-loop superfamily of ligand-gated ion channels (LGICs) and therefore differs structurally and functionally from all other 5-HT receptors (5-hydroxytryptamine, or serotonin receptors) which are G protein-coupled receptors. This ion channel is cation-selective and mediates neuronal depolarization and excitation within the central and peripheral nervous systems.